Fresh analysis suggests that individuals who stop using new GLP-1 drugs like Wegovy and Mounjaro can put back on shed pounds far faster than those who stop conventional diet and exercise plans.
Research printed in a major health publication demonstrates that while obese individuals can lose substantial amounts of their body weight while using the jabs, the weight is regained at an estimated rate of 0.8 kg per month after stopping.
"People purchasing such medications must be aware of the potential of fast rebound weight gain when the treatment concludes," stated lead investigator Dr. Susan Jebb.
Such speed of recovery suggests a return to pre-treatment weight in about one and a half years.
Analyzing Treatments
The study, which reviewed 37 of trials involving thousands of participants, compared the results of these new drugs with conventional dieting.
The team emphasize that individuals who shed pounds through dieting generally have a more gradual creep back—around 0.1 kg a month—once they finish.
Explaining the Quick Rebound
Nutrition scientists believe the mechanism of the jabs accounts for the accelerated rebound.
These medications copy a body's own chemical called GLP-1, which moderates hunger.
"Artificially providing GLP-1 concentrations far above than normal could lead to the system to generate a reduced amount of its own natural GLP-1, and could lessen sensitivity to its actions," noted Dr. Adam Collins, a nutrition specialist.
"Stopping of this medication results in hunger is no longer kept in check, making overeating a significant risk."
A Lifelong Condition?
Health authorities advise the jabs for people with weight-linked medical conditions, accompanied by recommended lifestyle changes.
Many experts contend that, due to the significant potential of weight regain, the treatment should be considered ongoing.
This opinion is reinforced by pharmaceutical companies, who state that the results "emphasize the chronic nature of excess weight," comparing it to managing conditions like diabetes.
Patient Accounts
People who have discontinued the medication explain a intense return of appetite.
"It was like a switch flipping and you become ravenous," described an individual.
The struggle is compounded if users have not adopted permanent lifestyle or habit modifications during therapy.
Growing Adoption
Recent estimates indicate that a significant number of adults in the UK have used weight-loss jabs in the past year, with interest continuing to grow.
- Use is higher among women compared to males.
- The middle-aged age group shows the highest usage rates.
- Many obtain the medications through private healthcare rather than public health services.
In conclusion, researchers stress that while these medications are effective agents for shedding pounds, they are not a permanent fix and lasting health benefits hinges on combined behavioural changes.
